Regulator ID target symbol target name hgnc_id ensembl_gene_id uniprot ID Entrez_id type type_class cell_line cell_id species cell_disease ICD_disease method PMID GSE log2FoldChange perturbation direction pvalue REG00005 IGHA1 Immunoglobulin heavy constant alpha 1 HGNC:5478 ENSG00000211895 IGHA1_HUMAN 3493 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 0.720656294 knock down up-regulate 0.040280795 REG00005 IGHA1 Immunoglobulin heavy constant alpha 1 HGNC:5478 ENSG00000211895 IGHA1_HUMAN 3493 Immunoglobulin gene Other RPMI-8226 cell line CVCL_0014 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 1.594662087 knock down up-regulate 0.036343278 REG00005 IGHA2 Immunoglobulin heavy constant alpha 2 (A2m marker) HGNC:5479 ENSG00000211890 IGHA2_HUMAN 3494 Immunoglobulin gene Other RPMI-8226 cell line CVCL_0014 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 1.137306052 knock down up-regulate 0.045036289 REG00005 IGHE Immunoglobulin heavy constant epsilon HGNC:5522 ENSG00000211891 IGHE_HUMAN 3497 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 0.893106424 knock down up-regulate 0.011261064 REG00005 IGHE Immunoglobulin heavy constant epsilon HGNC:5522 ENSG00000211891 IGHE_HUMAN 3497 Immunoglobulin gene Other RPMI-8226 cell line CVCL_0014 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 2.236155614 knock down up-regulate 0.041604386 REG00005 IGHG1 Immunoglobulin heavy constant gamma 1 (G1m marker) HGNC:5525 ENSG00000211896 IGHG1_HUMAN 3500 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 -5.180816477 knock down down-regulator 0.048900564 REG00005 IGHG2 Immunoglobulin heavy constant gamma 2 (G2m marker) HGNC:5526 ENSG00000211893 IGHG2_HUMAN 3501 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 -1.091469394 knock down down-regulator 0.046842388 REG00005 IGHG3 Immunoglobulin heavy constant gamma 3 (G3m marker) HGNC:5527 ENSG00000211897 IGHG3_HUMAN 3502 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 1.378763874 knock down up-regulate 0.001589115 REG00005 IGHG4 Immunoglobulin heavy constant gamma 4 (G4m marker) HGNC:5528 ENSG00000211892 IGHG4_HUMAN 3503 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 -2.73039105 knock down down-regulator 0.015302918 REG00005 IGHJ6 Immunoglobulin heavy joining 6 HGNC:5540 ENSG00000211900 . 28475 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 -1.818794097 knock down down-regulator 0.007706945 REG00005 IGKC Immunoglobulin kappa constant HGNC:5716 ENSG00000211592 IGKC_HUMAN 3514 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 -1.397753599 knock down down-regulator 0.013713079 REG00005 IGKV1D-17 Immunoglobulin kappa variable 1D-17 HGNC:5749 ENSG00000242766 KVD17_HUMAN 28900 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 -0.860065114 knock down down-regulator 0.022345506 REG00005 IGKV1D-43 Immunoglobulin kappa variable 1D-43 HGNC:5758 ENSG00000242580 KVD43_HUMAN 28891 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 -2.567110606 knock down down-regulator 0.025134498 REG00005 IGKV1D-8 Immunoglobulin kappa variable 1D-8 HGNC:5759 ENSG00000239819 KVD08_HUMAN 28904 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 -0.89642377 knock down down-regulator 0.01899364 REG00005 IGKV1OR2-108 Immunoglobulin kappa variable 1/OR2-108 (non-functional) HGNC:5767 ENSG00000231292 . 28862 Immunoglobulin gene Other THP1 CVCL_0006 Homo sapiens Acute myeloid leukemia 2A60: Acute myeloid leukaemia RNA-seq 32402251 GSE128574 -1.034472579 knock down down-regulator 0.035506578 REG00005 IGLC2 Immunoglobulin lambda constant 2 HGNC:5856 ENSG00000211677 IGLC2_HUMAN 3538 Immunoglobulin gene Other RPMI-8226 cell line CVCL_0014 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 -1.25566057 knock down down-regulator 0.03998464 REG00005 IGLC7 Immunoglobulin lambda constant 7 HGNC:5861 ENSG00000211685 IGLC7_HUMAN 28834 Immunoglobulin gene Other RPMI-8226 cell line CVCL_0014 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 -2.053023936 knock down down-regulator 0.011439778 REG00005 IGLJ1 Immunoglobulin lambda joining 1 HGNC:5863 ENSG00000211674 LJ01_HUMAN 28833 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 -0.826450385 knock down down-regulator 0.021240783 REG00005 IGLV1-51 Immunoglobulin lambda variable 1-51 HGNC:5882 ENSG00000211644 LV151_HUMAN 28820 Immunoglobulin gene Other Human islet-like organoids . Homo sapiens Healthy . RNA-seq 35851388 GSE163945 -0.85072311 knock out down-regulator 0.011032833 REG00005 IGLV6-57 Immunoglobulin lambda variable 6-57 HGNC:5927 ENSG00000211640 LV657_HUMAN 28778 Immunoglobulin gene Other Human islet-like organoids . Homo sapiens Healthy . RNA-seq 35851388 GSE163945 -0.846558829 knock out down-regulator 0.048624291 REG00005 IGLV6-57 Immunoglobulin lambda variable 6-57 HGNC:5927 ENSG00000211640 LV657_HUMAN 28778 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 -3.669299771 knock down down-regulator 0.046754624 REG00005 IGLV7-46 Immunoglobulin lambda variable 7-46 HGNC:5930 ENSG00000211649 LV746_HUMAN 28775 Immunoglobulin gene Other CAG cell line CVCL_D569 Homo sapiens Multiple myeloma 2A83: Multiple myeloma RNA-seq . GSE180214 -4.481891055 knock down down-regulator 0.047098239